Unveiling metabolic pathways involved in the extreme desiccation tolerance of an Atacama cyanobacterium
Published in Scientific Reports, 2023
In this study, we developed a genome-scale model (GEM; iGd895) to explore the metabolic capacity of G. dulcis undergoing desiccation. GEMs have been used to decipher microbial metabolism by integrating genomic information into a mathematical framework that simulates metabolism using optimization techniques, such as flux balance analysis (FBA). This technique allows for the prediction of cellular growth and production rates of metabolites under specified conditions. GEMs have been utilized for diverse applications, such as predicting enzyme functions, modeling microbial cell interactions9, and investigating microbial growth in various environmental contexts.
Recommended citation: Moore, R.A., Azua-Bustos, A., González-Silva, C. et al. Unveiling metabolic pathways involved in the extreme desiccation tolerance of an Atacama cyanobacterium. Sci Rep 13, 15767 (2023). https://doi.org/10.1038/s41598-023-41879-8 https://www.nature.com/articles/s41598-023-41879-8